• Bang Yeon Hwang
  • Mi Kyeong Lee
Bang Yeon Hwang


1992 B.S. College of Pharmacy, Chungbuk National University, Korea
1994 M.S. College of Pharmacy, Chungbuk National University, Korea
1999 Ph.D. College of Pharmacy, Chungbuk National University, Korea
1999-2001 Postdoc, Korea Research Institute of Bioscience and Biotechnology (KRIBB)
2001-2003 Postdoctoral Research Associate, College of Pharmacy, University of Illinois at Chicago, Chicago, Illinois, U.S.A.


Research Areas

1) Isolation and structure determination of new bioactive compounds from natural products

2) Activity-guided isolation of plant-derived anticancer and antiinflammatory agents

3) Development of NF-kB inhibitors from natural products


Selected Publications

1) Suppression of RelA/p65 transactivation activity by a lignoid manassantin isolated from Saururus chinensis, Biochem. Pharmacol., 69(10), 1925-1933 (2003).
2) Antimicrobial constituents from goldenseal (the Rhizomes of Hydrastis canadensis) against selected oral pathogens, Planta Med., 69(7), 623-627 (2003).
3) Cytotoxic triterpenes from the twigs of Celtis philippinensis, Phytochemistry, 62(2), 197-201 (2003)
4) Kaurane diterpene, kamebakaurin, inhibits NF-kB by directly targeting the DNA-binding activity of p50 and blocks the expression of antiapoptotic NF-kB target genes, J. Biol. Chem., 277(21), 18411-18420 (2002)
5) Two new furanoditerpenes from Saururus chinenesis and their effects on the activation of peroxisome proliferator-activated receptor gamma, J. Nat. Prod., 65(4), 616-617 (2002)

1) Novel use of diterpene compound as a therapeutic agent of inflammation, immune disease or cancer, PCT patent, Patent No. WO 02/47675 A1 (2002)

Mi Kyeong Lee


1988-1992: BS, College of Pharmacy, Seoul National University
1992-1994: MS, College of Pharmacy, Seoul National University
1994-2000: Ph.D, College of Pharmacy, Seoul National University



2000-2001: Post Doc. National Institute of Health, Korea
2001-2003: Post Doc. NIDDK, National Institute of Health, USA
2004-2005: Research associate, Research Institute of Pharmaceutical Science, Seoul National University
2006-2007: Director, Institute for Life Science, Elcom Science Co.Ltd.
2008-2008: Research Professor, Institute of Nano-Bio Technology, Ewha Womans University
2008-present: Assistant Professor, College of Pharmacy, Chungbuk National University


Selected Publications

1) Antifibrotic activity of triterpenoids from the aerial parts of Euscaphis japonica on hepatic stellate cells (2009) J Enz Inhib Med Chem, 24: 1276-1279
2) Determination and Identification of Nine Constituents in Siho-Gyeoji-Tang by HPLC-DAD and HPLC-MS/MS (2009) J Liq Chromatogr rel Technol, 32: 2122-2133
3) Pinusolide and 15-methoxypinusolidic acid attenuate the neurotoxic effect of staurosporine in primary rat cortical cultures. Br J Pharmacol 150: 65-71 (2007)


Research Areas

1) Bioactive compounds from natural resources

2) Structure activity relationship of derivatives

3) Evaluation of biological activity of natural products